The Laser-Assisted Medical Physics and Engineering (LAMPE) Laboratory team https://lampe.physics.carleton.ca/ develops non-invasive optical imaging techniques for rapid diagnostics, and to enable fundamental biophysics discovery.
Biodosimetry is an essential technique used to provide individual estimates of the absorbed dose of ionizing radiation through the detection of biological indicators. Current biodosimetry techniques are labour-intensive and time-consuming and hence not cost-effective. This project aims to develop a Raman spectroscopy-based technique to detect the biochemical response of blood exposed to varying doses of ionizing radiation. The student will acquire Raman spectral data from blood plasma and will analyze the data using different approaches such as multivariate analysis and machine learning for dose classification and identification of Raman biomarker bands.
Supervisor: Prof. Sangeeta Murugkar, smurugkar
physics [dot] carleton [dot] ca