Dr. Sangeeta Murugkar

I am interested in applying my background in studying light-matter interactions as well as experience in the photonics industry, to develop multimodal optical techniques that can be translated to the clinic for improving patient care. I am passionate about developing new optical tools for the rapid detection and treatment monitoring of diseases such as cancer.

 Selected Publications

• B. Hansson, C. H. Allen, S. Qutob, B. Behr, B. Nyiri, V. Chauhan and S. Murugkar, “Development of a flow cell based Raman spectroscopy technique to overcome photodegradation in human blood”, Biomedical Optics Express, 10 (5), pp. 2275-2288 (2019).

• Mikko J. Huttunen, Abdurahman Hassan, Curtis W. McCloskey, Sijyl Fasih, Jeremy Upham, Barbara Vanderhyden, Robert W. Boyd and Sangeeta Murugkar, “Automated classification of multiphoton microscopy images using deep learning”, J Biomed Opt. 23(6), 1-7 (2018).

• Christian Harry Allen, Achint Kumar, Balazs Nyiri, Sami Qutob, Vinita Chauhan and Sangeeta Murugkar, “Raman micro spectroscopy identifies nonlinear response of human lens epithelial cells exposed to ionizing radiation”, Phys. Med. Biol. 63, 025002 (2018). 

•  Simran Bahia, Erica Blais, Sangeeta Murugkar, Vinita Chauhan and Premkumari Kumarathasan, “Oxidative and nitrative stress-related changes in human lens epithelial cells following exposure to X-rays”, Int J Radiat Biol. 94(4), 366-373 (2018).

• H. Moradi, A. Ahmad, D. Shepherdson, N. H. Vuong, G. Niedbala, L. Eapen, B. Vanderhyden, B. Nyiri and S. Murugkar (2016). Raman micro-spectroscopy applied to treatment resistant and sensitive human ovarian cancer cells, J. Biophotonics 1–8 (2016) / DOI 10.1002/jbio.201600211.

• Sangeeta Murugkar and Robert W. Boyd (2016). Overview of second- and third-order nonlinear optical processes for deep tissue imaging. Editors: Lingyan Shi and Robert Alfano. Book Title: Deep Imaging in Tissue and Biomedical Materials using Linear and Non-linear Optical Methods (published, Pan Stanford Publishing, United States).

• Santa Borel, Emil A. Prikryl*, Nhung Vuong, James Jonkman, Barbara Vanderhyden, Brian C. Wilson and Sangeeta Murugkar, "Live-cell Raman microspectroscopy to differentiate between normal and malignant mouse ovarian surface epithelial cells", Analytical Methods, DOI: 10.1039/C5AY02462E (2015).

• Simon-Alexandre Lussier*, Hamid Moradi*, Alain Price* and Sangeeta Murugkar, "Imaging highly absorbing nanoparticles using photothermal microscopy", Proc. SPIE Vol. 9337 93370N1-5 (2015). 

• M. Naji*, S. Murugkar, H. Anis, "Determining optimum operating conditions of the polarization maintaining fiber with two far-lying zero dispersion wavelengths for CARS microscopy", Optics Express, 22(9), 10800-10814 (2014).

• J. Upham, I. De Leon, D. Grobnic, E. Ma*, MC Dicaire, SA Schulz, S. Murugkar, RW Boyd, "Enhancing optical field intensities in Gaussian-profile fiber Bragg gratings", Optics Letters 39(4), 849-52 (2014).

• B. Smith, M. Naji, S. Murugkar, Emilio Alarcon, C. Brideau, P. Stys, H. Anis, “Portable, miniaturized, fibre delivered, multimodal CARS exoscope”, Optics Express 21, 17161-17175 (2013).

• Sangeeta Murugkar, Israel De Leon, Matthew Horton, Hammam Qassim, Jonathan Leach and Robert W. Boyd, “Planar chiral metamaterials for biosensing applications”, Proc. SPIE 8597 85970Y (2013).

• S. Murugkar, B. Smith, P. Srivastava, A. Moica, C. Brideau, P. Stys, H. Anis, “Miniaturized multimodal CARS microscope based on MEMS scanning and a single laser source”, Optics Express 18, 23796 (2010) {selected for publication in the Virtual Journal of Biomedical Optics Vol. 6(1) (Jan 3 2011)}.

• S. Murugkar, C. Evans, S. Xie, H. Anis, “Chemically specific imaging of cryptosporidium oocysts using coherent anti-Stokes Raman scattering (CARS) microscopy”, Journal of microscopy 233, 244 - 250 (2009).

• S. Murugkar, C. Brideau, A. Ridsdale, M. Naji, P. Stys, H. Anis, “Coherent anti-Stokes Raman scattering microscopy using photonic crystal fiber with two closely lying zero dispersion wavelengths”, Optics Express 15, 14028 (2007).