Abstract:
I will review a few of the projects that I have been involved with to improve the spatial resolution of images first in nuclear medicine and then, with new Micro-Angiographic Fluoroscopic (MAF) detectors, in neurovascular imaging. I will discuss various metrics used to compare the new detectors with current ones and how the MAF concept has become a product distributed world-wide. Most recently I have been involved with improving temporal resolution of angiographic imaging sequences with a 1000 frame per second single photon counting x-ray detector that enables fine details of flow to be recorded for the first time. Flow in patient-specific 3D printed vascular models and estimations of velocity distributions in them using optical flow (OF) and x-ray particle image velocimetry (XPIV) will be demonstrated.