Dr. Gabriel Sawakuchi

Adjunct Research Professor
Tel: 
Email: 
gsawakuchiatmdanderson [dot] org

Research summary

Radiation measurements of therapeutic x-ray, electron, proton and heavy-ion beams, aiming on developing and establishing new, reliable and cost-effective dosimeters in the clinic

  • Apply the optically stimulated luminescence (OSL) technique in medicine

  • Characterize existing OSL materials to clinical radiation fields (x-rays, electrons, protons and heavy-ions)

  • Develop OSL readout protocols which minimize systematic uncertainties

  • Develop cost-effective, portable and reliable OSL readout equipments

  • Develop methods to measure radiation quality

Monte Carlo simulations of proton and heavy-ion therapeutic beams (hadron therapy), aiming on determining current limitations and uncertainties, and further developing the field of hadron therapy

  • Improve the accuracy of proton and heavy-ion analytical dose calculation models used by treatment planning systems

  • Improve and develop new nozzles’ designs for future proton and heavy-ion radiation therapy facilities

  • Investigate the response of dosimeters exposed to hadron therapy beams

 

Selected publications:

  1. G. O. Sawakuchi, D. Mirkovic, L. A. Perles, G. Ciangaru, N. Sahoo, X. R. Zhu, K. Suzuki, M. T. Gillin, R. Mohan and U. Titt. “An MCNPX model of a scanning proton beam therapy nozzle”, Med. Phys., 37, 4960-4970 (2010)
  2. G. O. Sawakuchi, N. Sahoo, P. Gasparian, M. Rodriguez, L. Archambault, U. Titt and E. G. Yukihara. “Determination of LET of therapeutic proton beams using the optically stimulated luminescence of Al2O3:C detectors”, Phys. Med. Biol., 55, 4963-4976 (2010)
  3. G. O. Sawakuchi, X. R. Zhu, F. Poenisch, K. Suzuki, U. Titt, A. Anand, R. Mohan, M. T. Gillin and N. Sahoo. “Experimental characterization of the low-dose envelope of proton pencil beams”, Phys. Med. Biol. 55, 3467-3478 (2010)
  4. E. G. Yukihara, P. B. R. Gasparian, G. O. Sawakuchi, C. Ruan, S. Ahmad, C. Kalavagunta, W.J. Clouse, N. Sahoo and U. Titt. “Medical applications of optically stimulated luminescence dosimeters (OSLDs)”, Radiat. Meas. 45, 658-662 (2010)
  5. G. O. Sawakuchi, U. Titt, D. Mirkovic, G. Ciangaru, X. R. Zhu, N. Sahoo, M. T. Gillin and R. Mohan. “Monte Carlo investigation of the low-dose envelope from scanned proton pencil beams”, Phys. Med. Biol. 55, 711-721 (2010)
  6. M. T. Gillin, N. Sahoo, M. Bues, G. Ciangaru, G. O. Sawakuchi, F. Poenisch, B. Arjomandy, C. Martin, U. Titt, K. Suzuki, A. R. Smith and X. R. Zhu. “Commissioning of the discrete spot scanning proton beam delivery System at the University of Texas M.D. Anderson Cancer Center, Proton Therapy Center, Houston”, Med. Phys. 37, 154-163 (2010)
  7. G. Ciangaru, N. Sahoo, X. R. Zhu, G. O. Sawakuchi and M. T. Gillin. “Computation of doses for large-angle Coulomb scattering of proton pencil beams”, Phys. Med. Biol. 54, 7285-7300 (2009)
  8. G. Reitz, T. Berger, P. Bilski, R. Facius, M. Hajek, V. Petrov, M. Puchalska, D. Zhou, J. Bossler, Y. Akatov, V. Shurshakov, P. Olko, M. Ptaszkiewicz, R. Bergmann, M. Fugger, N. Vana, R. Beaujean, S. Burmeister, D. Bartlett, L. Hager, J. Pálfalvi, J. Szabó, D. O’Sullivan, H. Kitamura, Y. Uchihori, N. Yasuda, A. Nagamatsu, H. Tawara, E. Benton, R. Gaza, S. McKeever, G. O. Sawakuchi, E. Yukihara, F. Cucinotta, E. Semones, N. Zapp, J. Miller, J. Dettmann. “Astronauts organ doses as inferred from measurements in a human phantom outside the ISS”, Radiation Research 171, 225-235 (2009)
  9. G. O. Sawakuchi, E. G. Yukihara, S. W. S. McKeever, R. Gaza, Eric R. Benton, Y. Uchi-hori, N. Yasuda and H. Kitamura. “Relative optically stimulated luminescence and thermoluminescence efficiencies of Al2O3:C dosimeters to heavy charged particles with energies relevant to space and radiotherapy dosimetry”, J. Appl. Phys. 104, 124903 (2008)
  10. G. O. Sawakuchi, U. Titt, D. Mirkovic and R. Mohan. “Density heterogeneities and the influence of multiple Coulomb and nuclear scatterings in the Bragg peak distal edge of pro-ton beams”, Phys. Med. Biol. 53, 4605-4619 (2008)
  11. G. O. Sawakuchi, E. G. Yukihara, S. W. S. McKeever and E. R. Benton. “Overlap of heavy charged particle tracks and the change in shape of optically stimulated luminescence curves of Al2O3:C”, Radiat. Meas. 43, 194-198 (2008)
  12. G. O. Sawakuchi, E. G. Yukihara, S. W. S. McKeever and E. R. Benton. “Optically stimulated luminescence fluence response of Al2O3:C exposed to different types of radiation”, Radiat. Meas. 43, 450-454 (2008)
  13. F. Vanhavere, J. L. Genicot, D. O’Sullivan, G. O. Sawakuchi, F. Spurny, E. G. Yukihara, and D. Zhou. “Dosimetry of biological experiments in space (DOBIES) with luminescence (OSL and TL) and track etch detectors”, Radiat. Meas. 43, 694-697 (2008)
  14. J. M. Edmund, C. E. Andersen, S. Greilich, G. O. Sawakuchi, E. G. Yukihara, M. Jain, W. Hajdas, and S. Mattsson. “Optically stimulated luminescence from Al2O3:C irradiated with 10-60 MeV protons”. Nucl. Instr. Meth. Phys. Res. A 580, 210-213 (2007).
  15. E. G. Yukihara, G. O. Sawakuchi, S. Guduru, S. W. S. McKeever, R. Gaza and E. R. Benton. “Application of the optically stimulated luminescence technique in space dosimetry”. Radiat. Meas. 41, 1126-1135 (2006)