OMPI Seminar and BBQ - Nick Majtenyi and Boguslaw Jarosz

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Date: 
Thursday, May 19, 2016

Time: 3:30-5:00 pm - Thursday 19 May 2016. Refreshments start at 3:15 pm.

Location: NRC - 1200 Montreal Road, Building M-36 - Kelvin Room (please check in at the front desk).


Program: 

1) Comparing input function measurements in DCE-MRI using phase and MOLLI

Nick Majtenyi, PhD student at Carleton University

Supervisor: Professor Ian Cameron

Abstract: Dynamic contrast-enhanced (DCE)-MRI is a quantitative imaging technique to obtain tissue hemodynamic information (e.g. tumours). Despite widespread clinical application of DCE-MRI, the technique suffers from a lack of standardization and accuracy, especially with respect to the concentration-versus-time of gadolinium (Gd) contrast agent in feeding arteries (the input function, IF). MR phase has a linear quantitative relationship with Gd concentration ([Gd]), making it ideal for measuring the first-pass of the IF, but is not considered accurate in the steady-state washout. Modified Look-Locker Inversion Recovery (MOLLI) is a fast and accurate method to measure T1 and has been validated to quantify typical [Gd] ranges experienced in the washout of the IF. This work compares two different methods to compute the IF used for DCE-MRI: (1) conventional phase-versus-time and (2) phase-versus-time combined with pre- and post-DCE MOLLI T1 measurements.

 

2) Ultrasound thermal therapy of cancer: Models and phantom measurements for brain

Boguslaw Jarosz, Emeritus Professor, Carleton University

Abstract: This talk presents issues regarding ultrasound thermal therapy of cancer. A design of an interstitial waveguide applicator will be presented and its physical characterization in a water phantom will be described. Results of measurements imply that for use in thermal therapy an array of applicators must be considered and such an array will be considered for treatment of brain tumours. First, FEA computations of blood flow effects on temperature pattern will be shown. This will be followed by details of a design of blood vessels incorporating phantom with its physical characterization. Heating patterns in the phantom will conclude the presentation.


3) End of season BBQ

Please don't forget to RSVP Bryan (Bryan.Muir(at)nrc-cnrc.gc.ca) if you will be attending the BBQ after the seminar (along with any dietary restrictions). Deadline for RSVP is May 16th.