Dal Granville, Richard Richardson and OMPI BBQ social

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Thursday, May 16, 2013
3:30 - 5:00 pm - May 16, 2013
NRC – 1200 Montreal Road, North Campus

We will be finishing off this season's seminar series with a BBQ at the NRC. To help in organizing this, we would like to have an idea of how many people are planning to come to the seminar and stay for the food afterwards. Please reply by May 13 to guarantee your share - Claudiu [dot] Cojocaruatnrc-cnrc [dot] gc [dot] ca (Claudiu . Cojocaru [at] nrc-cnrc . gc . ca). We will make every effort to accommodate special dietary needs (e.g. vegetarians) but only if we know in advance.


1.  “Measurement of average LET of proton therapy beams using optically stimulated luminescence detectors”

Dal Granville – Carleton University

Abstract: The biological response of tissue irradiated with heavy charged particle beams depends on both the absorbed dose in the tissue and the linear energy transfer (LET) of the beam. While absorbed dose is routinely measured using a variety of detectors, there is no device available for the routine measurement and verification of LET. This work aims to further develop the optically stimulated luminescence (OSL) technique, which is already well established for absorbed dose measurements, to allow for routine measurements of LET in heavy charged particle beams, specifically proton beams. This presentation will focus on the LET dependence of Al2O3:C OSL detectors, and a proof-of-concept experiment that demonstrates the feasibility of using these detectors for LET measurements of radiotherapy proton beams.

2. "Are Alpha- and Beta-Emitting Bone-Seeking Radionuclides Effective Treatments against Leukemia Stem Cells and Bone Metastases?”

Richard Richardson – Atomic Energy of Canada Limited (AECL)

Abstract: Studies are in progress with clinicians/scientists at Ottawa Hospital that are examining the fundamental effects of ionizing radiation on marrow stem cells, the source of common forms of leukemia and bone cancer. I will also describe the results of a Monte Carlo simulation with scientists at Purdue University, USA, which  initially indicated that the radiation dosimetry of bone metastases with bone-seeking radium-223 was effective and non-toxic, but not so when later allowance was made for the diffusion of radon-119.